Cart
sales@molnova.com
Amtolmetin guacil
CAS No. 87344-06-7
Amtolmetin guacil( —— )
Catalog No. M27126 CAS No. 87344-06-7
Amtolmetin guacil inhibits prostaglandin synthesis and cyclooxygenase. Amtolmetin guacil has similar NSAID properties like tolmetin with additional analgesic, antipyretic, and gastroprotective properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 45 | Get Quote |
|
| 10MG | 63 | Get Quote |
|
| 25MG | 103 | Get Quote |
|
| 50MG | 150 | Get Quote |
|
| 100MG | 223 | Get Quote |
|
| 500MG | 482 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameAmtolmetin guacil
-
NoteResearch use only, not for human use.
-
Brief DescriptionAmtolmetin guacil inhibits prostaglandin synthesis and cyclooxygenase. Amtolmetin guacil has similar NSAID properties like tolmetin with additional analgesic, antipyretic, and gastroprotective properties.
-
DescriptionAmtolmetin guacil inhibits prostaglandin synthesis and cyclooxygenase. Amtolmetin guacil has similar NSAID properties like tolmetin with additional analgesic, antipyretic, and gastroprotective properties.
-
In VitroAmtolmetin guacil (100 μM; 0-60 min) converts to TMT (Tolmetin, HY-B1799) along with MED5 (1-methyl-5-p-methylbenzoyl-pyrrol-2-acetamido aceticacid) in rat fresh plasma and rat liver microsomal, rapidly converts to MED5 and MED5 methyl ester without yielding TMT in human fresh plasma and human liver microsomes.
-
In VivoAnimal Model:Male Wistar ratsDosage:50 mg/kg Administration:p.o.; single dosage Result:Pharmacokinetic Parameters of Amtolmetin guacil in male Wistar rats.
-
Synonyms——
-
PathwayChromatin/Epigenetic
-
TargetCOX
-
RecptorUSP30
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number87344-06-7
-
Formula Weight420.465
-
Molecular FormulaC24H24N2O5
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCOc1ccccc1OC(=O)CNC(=O)Cc1ccc(C(=O)c2ccc(C)cc2)n1C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Arthur F Kluge, et al. Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg Med Chem Lett. 2018 Aug 15;28(15):2655-2659.
molnova catalog
related products
-
Sifalimumab
Sifalimumab (MEDI-545) is a monoclonal antibody that targets IFNα and suppresses abnormal immune activity by binding to interferon-alpha.Sifalimumab is used for the treatment of moderate to severe SLE.
-
BN-82451 2HCl
BN-82451 2HCl is a dual inhibitor of COX-1 and COX-2 and can be used to study Huntington's chorea and Parkinson's disease.
-
Tolfenamic Acid
Tolfenamic acid (TA) is one of the class of non-steroidal anti-inflammatory drugs (NSAIDs).
